MolNFT v1 · #2031 · protein
Topoisomerase II residues 409-1201
1BJT: “Topoisomerase II residues 409-1201”. X-ray diffraction, 6 pockets (best druggability 0.79). MolNFT v1 #2031 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1BJT
- Type
- protein
- Length
- 679 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Topoisomerase II
- EC
- 5.99.1.3
- UniProt
- P06786
- Pockets
- 6 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Topoisomerase II (EC 5.99.1.3) | protein | 679 | 42% helix, 17% strand | P06786 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 883 | 0.79 | 0.81 | 71 | empty |
| 2 | 187 | 0.49 | 0.76 | 28 | empty |
| 3 | 145 | 0.42 | 0.75 | 21 | empty |
| 4 | 80 | 0.33 | 0.74 | 15 | empty |
| 5 | 83 | 0.31 | 0.73 | 16 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06786
- Elsewhere: RCSB PDB 1BJT · PDBe 1BJT · UniProt P06786
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