MolNFT v1 · #20298 · protein

Three-dimensional structure of rat liver 3ALPHA- HYDROXYSTEROID(SLASH)DIHYDRODIOL dehydrogenase: a member of the aldo-keto reductase superfamily

1RAL · 3-alpha-hydroxysteroid dehydrogenase: “Three-dimensional structure of rat liver 3ALPHA- HYDROXYSTEROID(SLASH)DIHYDRODIOL dehydrogenase: a member of…”. X-ray diffraction, 5 pockets (best druggability 0.71). MolNFT v1 #20298 on…

PDB: 1RAL
Type: protein
Length: 308 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 3-alpha-hydroxysteroid dehydrogenase
EC: 1.1.1.50
UniProt: P23457
Pockets: 5 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	3-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.50)	protein	308	36% helix, 16% strand	P23457

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	484	0.71	0.81	59	empty
2	92	0.49	0.82	14	empty
3	65	0.39	0.79	13	empty
4	73	0.37	0.78	15	empty
5	66	0.32	0.76	19	empty

Compared structures

1RAL · Three-dimensional structure of rat liver 3ALPHA-HYDROXYSTEROID(SLASH)DIHYDRODIOL… · the same entry in another collection · chain A against A, TM-score 1.00
P23457 · AlphaFold monomer V2.0 prediction for 3-alpha-hydroxysteroid dehydrogenase (P23457) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23457
Elsewhere: RCSB PDB 1RAL · PDBe 1RAL · UniProt P23457

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