MolNFT v1 · #2026 · protein

Structure of phosphoserine aminotransferase from escherichia COLI

1BJN: “Structure of phosphoserine aminotransferase from escherichia COLI”. X-ray diffraction, 7 pockets (best druggability 0.68). MolNFT v1 #2026 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1BJN
Type: protein
Length: 720 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphoserine aminotransferase
EC: 2.6.1.52
UniProt: P23721
Pockets: 7 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Phosphoserine aminotransferase (EC 2.6.1.52)	protein	360	41% helix, 19% strand	P23721

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	420	0.68	0.80	39	empty
2	354	0.65	0.80	39	empty
3	111	0.44	0.78	18	empty
4	76	0.39	0.78	15	empty
5	53	0.33	0.78	14	empty

Interfaces

1 interface between chains.

A–B · 2373 Å² buried · 38 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (cofactor).

Compared structures

1BJN · Structure of phosphoserine aminotransferase from escherichia COLI · the same entry in another collection · chain A against A, TM-score 1.00
P23721 · AlphaFold monomer V2.0 prediction for phosphoserine aminotransferase (P23721) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23721
Elsewhere: RCSB PDB 1BJN · PDBe 1BJN · UniProt P23721

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