MolNFT v1 · #20250 · protein
Native structure of the B12-independent glycerol dehydratase from clostridium butyricum
1R8W: “Native structure of the B12-independent glycerol dehydratase from clostridium butyricum”. X-ray diffraction, 17 pockets (best druggability 0.81). MolNFT v1 #20250 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1R8W
- Type
- protein
- Length
- 1,572 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycerol dehydratase
- UniProt
- Q8GEZ8
- Pockets
- 17 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Glycerol dehydratase | protein | 786 | 52% helix, 9% strand | Q8GEZ8 |
Pockets
17 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 987 | 0.81 | 0.82 | 77 | empty |
| 2 | 56 | 0.72 | 0.99 | 27 | empty |
| 3 | 153 | 0.62 | 0.85 | 31 | empty |
| 4 | 162 | 0.61 | 0.84 | 31 | empty |
| 5 | 110 | 0.56 | 0.84 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1270 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 1R8W · Native structure of the B12-independent glycerol dehydratase from clostridium butyricum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8GEZ8
- Elsewhere: RCSB PDB 1R8W · PDBe 1R8W · UniProt Q8GEZ8
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