MolNFT v1 · #2025 · protein
Loc naks, a lambda 1 type light-chain dimer (bence-jones protein) crystallized in NAKSO4
1BJM · Loc - lambda 1 type light-chain dimer: “Loc naks, a lambda 1 type light-chain dimer (bence-jones protein) crystallized in NAKSO4”. X-ray diffraction, 4 pockets (best druggability 0.70). MolNFT v1 #2025 on GenesisL1: 3D structure…
- PDB
- 1BJM
- Type
- protein
- Length
- 432 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Loc - lambda 1 type light-chain dimer
- Pockets
- 4 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Loc - lambda 1 type light-chain dimer | protein | 216 | 6% helix, 49% strand | — |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 872 | 0.70 | 0.76 | 72 | empty |
| 2 | 139 | 0.48 | 0.78 | 25 | empty |
| 3 | 117 | 0.44 | 0.77 | 18 | empty |
| 4 | 51 | 0.32 | 0.77 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 2102 Ų buried · 28 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide, 2 modified (disulfide, cyclization).
Compared structures
- 1BJM · Loc naks, a lambda 1 type light-chain dimer (bence-jones protein) crystallized in NAKSO4 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1BJM · PDBe 1BJM
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