MolNFT v1 · #20031 · protein
Crystal structure of the B-cell lymphoma 6 (BCL6) btb domain to 2.2 ångström
1R28 · B-cell lymphoma 6 protein: “Crystal structure of the B-cell lymphoma 6 (BCL6) btb domain to 2.2 ångström”. X-ray diffraction, 2 pockets (best druggability 0.48). MolNFT v1 #20031 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1R28
- Type
- protein
- Length
- 244 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- B-cell lymphoma 6 protein
- UniProt
- P41182
- Pockets
- 2 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 57% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | B-cell lymphoma 6 protein | protein | 122 | 57% helix, 13% strand | P41182 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.48 | 0.80 | 18 | empty |
| 2 | 134 | 0.42 | 0.75 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1808 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 1R28 · Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom · the same entry in another collection · chain A against A, TM-score 1.00
- P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain A against A, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41182
- Elsewhere: RCSB PDB 1R28 · PDBe 1R28 · UniProt P41182
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