MolNFT v1 · #19853 · protein

Solution structure of the monomeric N67D mutant of bovine seminal ribonuclease

1QWQ: “Solution structure of the monomeric N67D mutant of bovine seminal ribonuclease”. Solution nmr, 1 pocket (best druggability 0.38). MolNFT v1 #19853 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QWQ
Type: protein
Length: 124 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribonuclease
EC: 3.1.27.5
UniProt: P00669
Pockets: 1 · best druggability 0.38

Structure

solution nmr · 1 distinct chain · 22% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribonuclease (EC 3.1.27.5)	protein	124	22% helix, 35% strand	P00669

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	89	0.38	0.76	21	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

1QWQ · Solution structure of the monomeric N67D mutant of Bovine Seminal Ribonuclease · the same entry in another collection · chain A against A, TM-score 1.00
P00669 · AlphaFold monomer V2.0 prediction for seminal ribonuclease (P00669) · a predicted model of the same protein · chain A against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00669
Elsewhere: RCSB PDB 1QWQ · PDBe 1QWQ · UniProt P00669

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