MolNFT v1 · #19827 · protein

Crystal structure of the S. cerevisiae YDR533C protein

1QVZ: “Crystal structure of the S. cerevisiae YDR533C protein”. X-ray diffraction, 5 pockets (best druggability 0.42). MolNFT v1 #19827 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QVZ
Type: protein
Length: 472 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: YDR533C protein
UniProt: Q04432
Pockets: 5 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	YDR533C protein	protein	236	41% helix, 16% strand	Q04432

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.42	0.79	18	empty
2	66	0.42	0.80	17	empty
3	65	0.36	0.78	16	empty
4	105	0.35	0.73	19	empty
5	65	0.31	0.75	13	empty

Interfaces

1 interface between chains.

A–B · 576 Å² buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 modified (engineered, oxidation).

Compared structures

1QVZ · Crystal structure of the S. cerevisiae YDR533c protein · the same entry in another collection · chain A against A, TM-score 1.00
Q04432 · AlphaFold monomer V2.0 prediction for glutathione-independent glyoxalase HSP31 (Q04432) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q04432
Elsewhere: RCSB PDB 1QVZ · PDBe 1QVZ · UniProt Q04432

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