MolNFT v1 · #19552 · protein
The 3-D structure of a trichoderma reesei B-mannanase from glycoside hydrolase family 5
1QNO · Endo-1,4-B-D-mannanase: “The 3-D structure of a trichoderma reesei B-mannanase from glycoside hydrolase family 5”. X-ray diffraction, 1 ligand (NAG), 1 pocket (best druggability 0.40). MolNFT v1 #19552 on GenesisL1: 3D structure…
- PDB
- 1QNO
- Type
- protein
- Length
- 344 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endo-1,4-B-D-mannanase
- EC
- 3.2.1.78
- UniProt
- Q99036
- Ligands
- NAG
- Pockets
- 1 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endo-1,4-B-D-mannanase (EC 3.2.1.78) | protein | 344 | 39% helix, 18% strand | Q99036 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 126 | 0.40 | 0.74 | 19 | TRS |
Modifications
Observed in the structure: 4 disulfide, 4 glycan (disulfide, N-glycosylation).
Compared structures
- 1QNO · The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5 · the same entry in another collection · chain A against A, TM-score 1.00
- Q99036 · AlphaFold monomer V2.0 prediction for mannan endo-1,4-beta- mannosidase a (Q99036) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99036
- Elsewhere: RCSB PDB 1QNO · PDBe 1QNO · UniProt Q99036
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