MolNFT v1 · #19548 · protein

Truncated human GROB[5-73], NMR, 20 structures

1QNK · C-X-C motif chemokine 2: “Truncated human GROB[5-73], NMR, 20 structures”. Solution nmr, 1 pocket (best druggability 0.44). MolNFT v1 #19548 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QNK
Type: protein
Length: 138 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C-X-C motif chemokine 2
UniProt: P19875
Pockets: 1 · best druggability 0.44

Structure

solution nmr · 1 distinct chain · 0% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	C-X-C motif chemokine 2	protein	69	0% helix, 26% strand	P19875

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	72	0.44	0.81	15	empty

Interfaces

1 interface between chains.

A–B · 755 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

1QNK · Truncated human GROB[5-73], NMR, 20 structures · the same entry in another collection · chain A against A, TM-score 1.00
P19875 · AlphaFold monomer V2.0 prediction for C-X-C motif chemokine 2 (P19875) · a predicted model of the same protein · chain B against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19875
Elsewhere: RCSB PDB 1QNK · PDBe 1QNK · UniProt P19875

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