GL1X · GenesisL1 explorer

MolNFT v1 · #19523 · protein

Duck carboxypeptidase D domain II

1QMU · Carboxypeptidase GP180 residues 503-882: “Duck carboxypeptidase D domain II”. X-ray diffraction, 4 ligands (NAG, MAN, ZN), 3 pockets (best druggability 0.52). MolNFT v1 #19523 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
1QMU
Type
protein
Length
380 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Carboxypeptidase GP180 residues 503-882
UniProt
Q90240
Ligands
NAG, MAN, ZN, SO4
Pockets
3 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ACarboxypeptidase GP180 residues 503-882protein38028% helix, 26% strandQ90240

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains A
  • MAN · alpha-D-mannopyranose · sugar · 2 copies
  • ZN · Zinc ion · metal · chains A
  • SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1690.520.8621SO4, ZN
2730.440.8122empty
3830.370.7617empty

Modifications

Observed in the structure: 3 glycan, 1 disulfide (N-glycosylation, disulfide).

Compared structures

  • 1QMU · Duck carboxypeptidase D domain II · the same entry in another collection · chain A against A, TM-score 1.00
  • Q90240 · AlphaFold monomer V2.0 prediction for carboxypeptidase D (Q90240) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.