MolNFT v1 · #19343 · protein

Chloramphenicol phosphotransferase from streptomyces venezuelae

1QHN: “Chloramphenicol phosphotransferase from streptomyces venezuelae”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.68). MolNFT v1 #19343 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QHN
Type: protein
Length: 178 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chloramphenicol phosphotransferase
EC: 2.7.1.-
UniProt: Q56148
Ligands: SO4
Pockets: 1 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chloramphenicol phosphotransferase (EC 2.7.1.-)	protein	178	46% helix, 19% strand	Q56148

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	364	0.68	0.81	36	SO4

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

1QHN · Chloramphenicol phosphotransferase from streptomyces venezuelae · the same entry in another collection · chain A against A, TM-score 1.00
Q56148 · AlphaFold monomer V2.0 prediction for chloramphenicol 3-O phosphotransferase (Q56148) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q56148
Elsewhere: RCSB PDB 1QHN · PDBe 1QHN · UniProt Q56148

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