MolNFT v1 · #19315 · protein

Human spliceosomal protein U5-15KD

1QGV: “Human spliceosomal protein U5-15KD”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #19315 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QGV
Type: protein
Length: 130 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Spliceosomal protein U5-15KD
UniProt: P83876
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Spliceosomal protein U5-15KD	protein	130	32% helix, 23% strand	P83876

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.29	0.74	12	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1QGV · Human spliceosomal protein U5-15KD · the same entry in another collection · chain A against A, TM-score 1.00
P83876 · AlphaFold monomer V2.0 prediction for thioredoxin-like protein 4A (P83876) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P83876
Elsewhere: RCSB PDB 1QGV · PDBe 1QGV · UniProt P83876

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