MolNFT v1 · #19189 · protein

Low temperature structure of pokeweed antiviral protein

1QCG: “Low temperature structure of pokeweed antiviral protein”. X-ray diffraction, 1 pocket (best druggability 0.77). MolNFT v1 #19189 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QCG
Type: protein
Length: 524 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pokeweed antiviral protein
UniProt: P10297
Pockets: 1 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Pokeweed antiviral protein	protein	262	38% helix, 24% strand	P10297

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	792	0.77	0.81	71	empty

Interfaces

1 interface between chains.

A–B · 499 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

1QCG · Low temperature structure of pokeweed antiviral protein · the same entry in another collection · chain A against A, TM-score 1.00
P10297 · AlphaFold monomer V2.0 prediction for antiviral protein I (P10297) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10297
Elsewhere: RCSB PDB 1QCG · PDBe 1QCG · UniProt P10297

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.