MolNFT v1 · #19164 · protein
Fab E8B antibody, X-ray structure at 2.37 ångströms resolution
1QBM: “Fab E8B antibody, X-ray structure at 2.37 ångströms resolution”. X-ray diffraction, 3 pockets (best druggability 0.63). MolNFT v1 #19164 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1QBM
- Type
- protein
- Length
- 433 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E8B antibody
- Pockets
- 3 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | E8B antibody | protein | 214 | 5% helix, 51% strand | — |
| H | E8B antibody | protein | 219 | 7% helix, 52% strand | — |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 531 | 0.63 | 0.76 | 44 | empty |
| 2 | 94 | 0.39 | 0.76 | 19 | empty |
| 3 | 122 | 0.39 | 0.74 | 19 | empty |
Interfaces
1 interface between chains.
- L–H · 2109 Ų buried · 20 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 1QBM · Fab E8B antibody, X-ray structure at 2.37 ångströms resolution · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1QBM · PDBe 1QBM
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