MolNFT v1 · #191519 · protein
Crystal structure of RNA helicase from genotype 1B hepatitis C virus: mechanism of unwinding duplex RNA
8OHM: “Crystal structure of RNA helicase from genotype 1B hepatitis C virus: mechanism of unwinding duplex RNA”. X-ray diffraction, 4 pockets (best druggability 0.50). MolNFT v1 #191519 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 8OHM
- Type
- protein
- Length
- 435 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA helicase
- UniProt
- P26663
- Pockets
- 4 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA helicase | protein | 435 | 33% helix, 21% strand | P26663 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 241 | 0.50 | 0.75 | 30 | empty |
| 2 | 102 | 0.44 | 0.79 | 18 | empty |
| 3 | 61 | 0.43 | 0.82 | 19 | empty |
| 4 | 108 | 0.39 | 0.75 | 23 | empty |
Compared structures
- 8OHM · Crystal structure of RNA helicase from genotype 1B hepatitis C virus: mechanism of… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26663
- Elsewhere: RCSB PDB 8OHM · PDBe 8OHM · UniProt P26663
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