MolNFT v1 · #191307 · protein
Arginase domain of ornithine DECARBOXYLASE/ARGINASE from fusobacterium nucleatum
8D27: “Arginase domain of ornithine DECARBOXYLASE/ARGINASE from fusobacterium nucleatum”. X-ray diffraction, 4 pockets (best druggability 0.63). MolNFT v1 #191307 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8D27
- Type
- protein
- Length
- 562 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Arginase
- UniProt
- Q8RG18
- Pockets
- 4 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Arginase | protein | 281 | 42% helix, 16% strand | Q8RG18 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 161 | 0.63 | 0.85 | 21 | empty |
| 2 | 122 | 0.46 | 0.78 | 17 | empty |
| 3 | 77 | 0.38 | 0.78 | 15 | empty |
| 4 | 57 | 0.35 | 0.78 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1167 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 8D27 · Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8RG18
- Elsewhere: RCSB PDB 8D27 · PDBe 8D27 · UniProt Q8RG18
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.