MolNFT v1 · #19126 · protein

Crystal structure of perchloric acid soluble protein-a translational inhibitor

1QAH: “Crystal structure of perchloric acid soluble protein-a translational inhibitor”. X-ray diffraction, 3 pockets (best druggability 0.50). MolNFT v1 #19126 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1QAH
Type: protein
Length: 264 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Perchloric acid soluble protein
UniProt: P52759
Pockets: 3 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Perchloric acid soluble protein	protein	132	27% helix, 30% strand	P52759

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	108	0.50	0.81	24	empty
2	58	0.35	0.78	17	empty
3	65	0.33	0.76	20	empty

Interfaces

1 interface between chains.

A–B · 357 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

1QAH · Crystal structure of perchloric acid soluble protein-a translational inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
P52759 · AlphaFold monomer V2.0 prediction for 2-IMINOBUTANOATE/2-iminopropanoate deaminase… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52759
Elsewhere: RCSB PDB 1QAH · PDBe 1QAH · UniProt P52759

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