MolNFT v1 · #191139 · protein
Crystal structure of the major guinea pig allergen cav P 1.0101 part of the lipocalin family
8A0D · Allergen lipocalin cav P 1 isoform 1: “Crystal structure of the major guinea pig allergen cav P 1.0101 part of the lipocalin family”. X-ray diffraction, 20 pockets (best druggability 0.83). MolNFT v1 #191139 on GenesisL1: 3D…
- PDB
- 8A0D
- Type
- protein
- Length
- 735 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Allergen lipocalin cav P 1 isoform 1
- UniProt
- A0A484HM70
- Pockets
- 20 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 12% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E | Allergen lipocalin cav P 1 isoform 1 | protein | 147 | 12% helix, 46% strand | A0A484HM70 |
Pockets
20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 154 | 0.83 | 0.98 | 24 | empty |
| 2 | 145 | 0.83 | 0.98 | 24 | empty |
| 3 | 144 | 0.83 | 0.98 | 24 | empty |
| 4 | 141 | 0.83 | 0.99 | 22 | empty |
| 5 | 140 | 0.83 | 0.99 | 24 | empty |
Interfaces
4 interfaces between chains.
- D–E · 711 Ų buried · 9 hydrogen bonds · protein-protein
- C–D · 710 Ų buried · 10 hydrogen bonds · protein-protein
- B–C · 706 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 698 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 disulfide (disulfide).
Compared structures
- 8A0D · Crystal structure of the major guinea pig allergen Cav p 1.0101 part of the lipocalin… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A484HM70
- Elsewhere: RCSB PDB 8A0D · PDBe 8A0D · UniProt A0A484HM70
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