MolNFT v1 · #191137 · protein
Crystal structure of poplar glutathione transferase U20 in complex with glutathione
8A08: “Crystal structure of poplar glutathione transferase U20 in complex with glutathione”. X-ray diffraction, 1 ligand (GSH), 3 pockets (best druggability 0.52). MolNFT v1 #191137 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 8A08
- Type
- protein
- Length
- 215 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione transferase
- EC
- 2.5.1.18
- UniProt
- D2X9R3
- Ligands
- GSH
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 58% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutathione transferase (EC 2.5.1.18) | protein | 215 | 58% helix, 9% strand | D2X9R3 |
Ligands and binding sites
- GSH · Glutathione · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 213 | 0.52 | 0.76 | 20 | GSH |
| 2 | 63 | 0.35 | 0.77 | 11 | empty |
| 3 | 61 | 0.32 | 0.76 | 14 | empty |
Compared structures
- 8A08 · Crystal structure of poplar glutathione transferase U20 in complex with glutathione · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D2X9R3
- Elsewhere: RCSB PDB 8A08 · PDBe 8A08 · UniProt D2X9R3
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