MolNFT v1 · #19105 · protein
Solution structure of the mature HIV-1 protease monomer
1Q9P: “Solution structure of the mature HIV-1 protease monomer”. Solution nmr, 2 pockets (best druggability 0.62). MolNFT v1 #19105 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1Q9P
- Type
- protein
- Length
- 95 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- HIV-1 protease
- EC
- 3.4.23.16
- UniProt
- P04587
- Pockets
- 2 · best druggability 0.62
Structure
solution nmr · 1 distinct chain · 4% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | HIV-1 protease (EC 3.4.23.16) | protein | 95 | 4% helix, 45% strand | P04587 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.62 | 0.87 | 30 | empty |
| 2 | 50 | 0.27 | 0.74 | 13 | empty |
Compared structures
- 1Q9P · Solution structure of the mature HIV-1 protease monomer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04587
- Elsewhere: RCSB PDB 1Q9P · PDBe 1Q9P · UniProt P04587
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.