MolNFT v1 · #191008 · protein + RNA
RNA binding induces an allosteric switch in CYP33 to repress MLL1 mediated transcription regulation
7ZEX · Isoform 3 of peptidyl-prolyl cis-trans isomerase E: “RNA binding induces an allosteric switch in CYP33 to repress MLL1 mediated transcription regulation”. Solution nmr. MolNFT v1 #191008 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7ZEX
- Type
- protein + RNA
- Length
- 101 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isoform 3 of peptidyl-prolyl cis-trans isomerase E; RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3')
- EC
- 5.2.1.8
- UniProt
- Q9UNP9
Structure
solution nmr · 2 distinct chains · 24% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isoform 3 of peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) | protein | 93 | 24% helix, 25% strand | Q9UNP9 |
| B | RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3') | rna | 8 | — | — |
Interfaces
1 interface between chains.
- A–B · 1060 Ų buried · 37 hydrogen bonds · protein-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UNP9
- Elsewhere: RCSB PDB 7ZEX · PDBe 7ZEX · UniProt Q9UNP9
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