MolNFT v1 · #190558 · protein

Crystal structure of cbp bromodomain liganded with CCS151

7XHE: “Crystal structure of cbp bromodomain liganded with CCS151”. X-ray diffraction, 1 ligand (JHF). MolNFT v1 #190558 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7XHE
Type: protein
Length: 233 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q92793
Ligands: JHF

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	121	—	Q92793
B	—	protein	112	—	Q92793

Ligands and binding sites

JHF · (6S)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]-1-(3-fluoranyl-4-methoxy-phenyl)piperidin-2-one · ligand · 2 copies · chains A, B
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7XHE · Crystal structure of CBP bromodomain liganded with CCS151 · the same entry in another collection · chain A against A, TM-score 1.00
Q92793 · AlphaFold monomer V2.0 prediction for creb-binding protein (Q92793) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92793
Elsewhere: RCSB PDB 7XHE · PDBe 7XHE · UniProt Q92793

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