MolNFT v1 · #190554 · protein

Structure of GEMIN5 C-terminal region (protomer)

7XGR · Gem-associated protein 5: “Structure of GEMIN5 C-terminal region (protomer)”. Electron microscopy, 3 pockets (best druggability 0.43). MolNFT v1 #190554 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7XGR
Type: protein
Length: 546 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Gem-associated protein 5
UniProt: Q8TEQ6
Pockets: 3 · best druggability 0.43

Structure

electron microscopy · 1 distinct chain · 73% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Gem-associated protein 5	protein	546	73% helix, 0% strand	Q8TEQ6

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	114	0.43	0.77	21	empty
2	68	0.34	0.76	15	empty
3	57	0.27	0.73	15	empty

Compared structures

7XGR · Structure of Gemin5 C-terminal region (protomer) · the same entry in another collection · chain A against A, TM-score 1.00
Q8TEQ6 · AlphaFold monomer V2.0 prediction for gem-associated protein 5 (Q8TEQ6) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TEQ6
Elsewhere: RCSB PDB 7XGR · PDBe 7XGR · UniProt Q8TEQ6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.