MolNFT v1 · #190510 · protein
Crystal structure of potato 14-3-3 protein ST14F
7XBQ · Putative 14-3-3 protein: “Crystal structure of potato 14-3-3 protein ST14F”. X-ray diffraction, 8 pockets (best druggability 0.56). MolNFT v1 #190510 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7XBQ
- Type
- protein
- Length
- 701 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative 14-3-3 protein
- UniProt
- P93785
- Pockets
- 8 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 82% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Putative 14-3-3 protein | protein | 233 | 83% helix, 0% strand | P93785 |
| B | Putative 14-3-3 protein | protein | 235 | 82% helix, 0% strand | P93785 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 303 | 0.56 | 0.76 | 49 | empty |
| 2 | 195 | 0.47 | 0.75 | 20 | empty |
| 3 | 169 | 0.47 | 0.76 | 20 | empty |
| 4 | 55 | 0.45 | 0.84 | 15 | empty |
| 5 | 162 | 0.44 | 0.75 | 20 | empty |
Interfaces
2 interfaces between chains.
- A–B · 628 Ų buried · 17 hydrogen bonds · protein-protein
- A–C · 589 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 7XBQ · Crystal structure of potato 14-3-3 protein St14f · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P93785
- Elsewhere: RCSB PDB 7XBQ · PDBe 7XBQ · UniProt P93785
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