GL1X · GenesisL1 explorer

MolNFT v1 · #190245 · protein

SARS-cov-2 omicron variant spike trimer complexed with ACE2

7WPA: “SARS-cov-2 omicron variant spike trimer complexed with ACE2”. Electron microscopy, 3 ligands (NAG, ZN, CL). MolNFT v1 #190245 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7WPA
Type
protein
Length
3,774 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P0DTC2, Q9BYF1
Ligands
NAG, ZN, CL

Structure

electron microscopy · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B—protein1061—P0DTC2
C—protein1057—P0DTC2
D—protein595—Q9BYF1

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 45 copies · chains A, B, C, D
  • ZN · Zinc ion · metal · chains D
  • CL · Chloride ion · ion · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7WPA · SARS-CoV-2 Omicron Variant SPIKE trimer complexed with ACE2 · the same entry in another collection · chain B against B, TM-score 1.00
  • 3SCI · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain D against A, TM-score 0.92
  • 3SCI · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain D against A, TM-score 0.92
  • 3SCJ · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain D against A, TM-score 0.92
  • 3SCJ · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain D against A, TM-score 0.92
  • 3SCK · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain D against A, TM-score 0.92
  • 3SCK · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain D against A, TM-score 0.92
  • Q9BYF1 · AlphaFold monomer V2.0 prediction for angiotensin-converting enzyme 2 (Q9BYF1) · a predicted model of the same protein · chain D against A, TM-score 0.90

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