MolNFT v1 · #190234 · protein
Crystal structure of hsa-myr complex soaked with cisplatin for one week
7WOJ · Albumin: “Crystal structure of hsa-myr complex soaked with cisplatin for one week”. X-ray diffraction, 2 ligands (CPT, MYR), 8 pockets (best druggability 0.85). MolNFT v1 #190234 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7WOJ
- Type
- protein
- Length
- 567 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Albumin
- UniProt
- P02768
- Ligands
- CPT, MYR
- Pockets
- 8 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Albumin | protein | 567 | 71% helix, 0% strand | P02768 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 281 | 0.85 | 0.95 | 50 | MYR |
| 2 | 348 | 0.78 | 0.88 | 37 | CPT, MYR |
| 3 | 733 | 0.77 | 0.81 | 64 | CPT, MYR |
| 4 | 323 | 0.72 | 0.84 | 36 | MYR |
| 5 | 223 | 0.64 | 0.82 | 38 | CPT, MYR |
Modifications
Observed in the structure: 16 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02768
- Elsewhere: RCSB PDB 7WOJ · PDBe 7WOJ · UniProt P02768
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