MolNFT v1 · #19014 · protein
X-ray structure of monoamine oxidase regulatory protein from archaeoglobus fulgius
1Q6W · Monoamine oxidase regulatory protein, putative: “X-ray structure of monoamine oxidase regulatory protein from archaeoglobus fulgius”. X-ray diffraction, 20 pockets (best druggability 0.85). MolNFT v1 #19014 on GenesisL1: 3D…
- PDB
- 1Q6W
- Type
- protein
- Length
- 1,802 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Monoamine oxidase regulatory protein, putative
- UniProt
- O28346
- Pockets
- 20 · best druggability 0.85
Structure
x-ray diffraction · 3 distinct chains · 28% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D, E, F | Monoamine oxidase regulatory protein, putative | protein | 151 | 28% helix, 39% strand | O28346 |
| C | Monoamine oxidase regulatory protein, putative | protein | 153 | 28% helix, 37% strand | O28346 |
| G, H, I, J, K, L | Monoamine oxidase regulatory protein, putative | protein | 149 | 29% helix, 38% strand | O28346 |
Pockets
20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 178 | 0.85 | 0.99 | 24 | empty |
| 2 | 170 | 0.85 | 0.99 | 23 | empty |
| 3 | 386 | 0.82 | 0.90 | 50 | empty |
| 4 | 413 | 0.82 | 0.90 | 55 | empty |
| 5 | 355 | 0.81 | 0.90 | 43 | empty |
Interfaces
32 interfaces between chains.
- G–H · 1559 Ų buried · 15 hydrogen bonds · protein-protein
- K–L · 1549 Ų buried · 18 hydrogen bonds · protein-protein
- C–D · 1542 Ų buried · 18 hydrogen bonds · protein-protein
- I–J · 1541 Ų buried · 15 hydrogen bonds · protein-protein
- E–F · 1534 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 24 modified (engineered).
Compared structures
- 1Q6W · X-Ray structure of Monoamine oxidase regulatory protein from Archaeoglobus fulgius · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O28346
- Elsewhere: RCSB PDB 1Q6W · PDBe 1Q6W · UniProt O28346
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