MolNFT v1 · #190009 · protein

Murj inward closed form

7WAW · Lipid II flippase murj: “Murj inward closed form”. X-ray diffraction, 5 pockets (best druggability 0.84). MolNFT v1 #190009 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7WAW
Type: protein
Length: 496 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipid II flippase murj
Pockets: 5 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 83% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipid II flippase murj	protein	496	83% helix, 0% strand	—

Ligands and binding sites

OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	947	0.84	0.85	99	OLC
2	172	0.55	0.79	22	OLC
3	73	0.47	0.82	14	empty
4	112	0.42	0.76	19	OLC
5	50	0.26	0.73	11	empty

Compared structures

7WAW · MurJ inward closed form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7WAW · PDBe 7WAW

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