MolNFT v1 · #189959 · protein
The crystal structure of human ABL1 kinase domain in complex with ABL1-A11
7W7X: “The crystal structure of human ABL1 kinase domain in complex with ABL1-A11”. X-ray diffraction, 1 ligand (8DW). MolNFT v1 #189959 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7W7X
- Type
- protein
- Length
- 531 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00519
- Ligands
- 8DW
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 267 | — | P00519 |
| B | — | protein | 264 | — | P00519 |
Ligands and binding sites
- 8DW · 5-[5-(dimethylcarbamoyl)pyridin-3-yl]-3-(5-fluorosulfonyloxy-2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7W7X · The crystal structure of human abl1 kinase domain in complex with ABL1-A11 · the same entry in another collection · chain A against A, TM-score 1.00
- P00519 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase ABL1 (P00519) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00519
- Elsewhere: RCSB PDB 7W7X · PDBe 7W7X · UniProt P00519
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