MolNFT v1 · #189877 · protein

Crystal structure of human SUV3 monomer

7W1R · ATP-dependent RNA helicase SUPV3L1, mitochondrial: “Crystal structure of human SUV3 monomer”. X-ray diffraction, 9 pockets (best druggability 0.74). MolNFT v1 #189877 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7W1R
Type: protein
Length: 519 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ATP-dependent RNA helicase SUPV3L1, mitochondrial
EC: 3.6.4.13
UniProt: Q8IYB8
Pockets: 9 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13)	protein	519	45% helix, 9% strand	Q8IYB8

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	528	0.74	0.82	62	empty
2	204	0.63	0.83	34	empty
3	283	0.60	0.79	26	empty
4	174	0.60	0.82	23	empty
5	148	0.57	0.82	20	empty

Compared structures

7W1R · Crystal structure of human Suv3 monomer · the same entry in another collection · chain A against A, TM-score 1.00
Q8IYB8 · AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase SUPV3L1, mitochondrial… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8IYB8
Elsewhere: RCSB PDB 7W1R · PDBe 7W1R · UniProt Q8IYB8

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