MolNFT v1 · #189690 · protein
De novo designed protein based on 1R26
7VQW: “De novo designed protein based on 1R26”. X-ray diffraction, 5 pockets (best druggability 0.49). MolNFT v1 #189690 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7VQW
- Type
- protein
- Length
- 232 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- De novo designed protein
- Pockets
- 5 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | De novo designed protein | protein | 116 | 38% helix, 25% strand | — |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.49 | 0.86 | 15 | empty |
| 2 | 176 | 0.49 | 0.77 | 16 | empty |
| 3 | 58 | 0.49 | 0.85 | 13 | empty |
| 4 | 105 | 0.37 | 0.74 | 18 | empty |
| 5 | 105 | 0.37 | 0.74 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 256 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 7VQW · de novo designed protein based on 1r26 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7VQW · PDBe 7VQW
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