MolNFT v1 · #189670 · protein

The apo-state ATALMT1 structure at pH 7.5(ALMT1APO/PH7.5)

7VQ4 · Aluminum-activated malate transporter 1: “The apo-state ATALMT1 structure at pH 7.5(ALMT1APO/PH7.5)”. Electron microscopy, 10 pockets (best druggability 0.74). MolNFT v1 #189670 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 7VQ4
Type: protein
Length: 800 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aluminum-activated malate transporter 1
UniProt: Q9SJE9
Pockets: 10 · best druggability 0.74

Structure

electron microscopy · 1 distinct chain · 77% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Aluminum-activated malate transporter 1	protein	400	77% helix, 1% strand	Q9SJE9

Pockets

10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1187	0.74	0.77	88	empty
2	51	0.67	0.96	16	empty
3	323	0.59	0.77	38	empty
4	299	0.58	0.77	34	empty
5	184	0.56	0.80	30	empty

Interfaces

1 interface between chains.

A–B · 3300 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

7VQ4 · The apo-state AtALMT1 structure at pH 7.5(ALMT1apo/pH7.5) · the same entry in another collection · chain A against A, TM-score 1.00
Q9SJE9 · AlphaFold monomer V2.0 prediction for aluminum-activated malate transporter 1 (Q9SJE9) · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9SJE9
Elsewhere: RCSB PDB 7VQ4 · PDBe 7VQ4 · UniProt Q9SJE9

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