MolNFT v1 · #189597 · protein

Crystal structure of the MTDMI1 gating ring

7VM8 · Ion channel DMI1: “Crystal structure of the MTDMI1 gating ring”. X-ray diffraction, 6 pockets (best druggability 0.76). MolNFT v1 #189597 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7VM8
Type: protein
Length: 505 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ion channel DMI1
UniProt: Q6RHR6
Pockets: 6 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ion channel DMI1	protein	505	33% helix, 22% strand	Q6RHR6

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	97	0.76	0.97	25	empty
2	160	0.53	0.80	24	empty
3	173	0.48	0.76	21	empty
4	151	0.46	0.77	25	empty
5	108	0.39	0.76	26	empty

Compared structures

7VM8 · Crystal structure of the MtDMI1 gating ring · the same entry in another collection · chain A against A, TM-score 1.00
Q6RHR6 · AlphaFold monomer V2.0 prediction for ion channel DMI1 (Q6RHR6) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6RHR6
Elsewhere: RCSB PDB 7VM8 · PDBe 7VM8 · UniProt Q6RHR6

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