MolNFT v1 · #189217 · protein

Crystal structure of the spnl

7V6H · Cyclopropane fatty-acyl-phospholipid synthase-like…: “Crystal structure of the spnl”. X-ray diffraction, 1 ligand (SAH), 4 pockets (best druggability 0.69). MolNFT v1 #189217 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 7V6H
Type: protein
Length: 534 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase
UniProt: A0A2N3Y640
Ligands: SAH
Pockets: 4 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase	protein	267	48% helix, 21% strand	A0A2N3Y640

Ligands and binding sites

SAH · S-adenosyl-L-homocysteine · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	517	0.69	0.79	58	SAH
2	436	0.66	0.79	55	SAH
3	218	0.52	0.77	28	empty
4	72	0.36	0.77	19	empty

Interfaces

1 interface between chains.

A–B · 460 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

7V6H · Crystal Structure of the SpnL · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2N3Y640
Elsewhere: RCSB PDB 7V6H · PDBe 7V6H · UniProt A0A2N3Y640

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.