MolNFT v1 · #189203 · protein
ACE2 -targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker
7V61: “ACE2 -targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker”. Electron microscopy, 2 ligands (NAG, ZN). MolNFT v1 #189203 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7V61
- Type
- protein
- Length
- 3,586 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q695T7, Q9BYF1
- Ligands
- NAG, ZN
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 605 | — | Q695T7 |
| B, D | — | protein | 751 | — | Q9BYF1 |
| H, I | — | protein | 223 | — | — |
| K, M | — | protein | 214 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 38 copies · chains A, B, C, D
- ZN · Zinc ion · metal · 2 copies · chains B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7V61 · ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker · the same entry in another collection · chain A against A, TM-score 1.00
- Q695T7 · AlphaFold monomer V2.0 prediction for sodium-dependent neutral amino acid transporter… · a predicted model of the same protein · chain A against A, TM-score 0.98
- Q9BYF1 · AlphaFold monomer V2.0 prediction for angiotensin-converting enzyme 2 (Q9BYF1) · a predicted model of the same protein · chain D against A, TM-score 0.95
- 3SCJ · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain B against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q695T7
- Every structure of UniProt Q9BYF1
- Elsewhere: RCSB PDB 7V61 · PDBe 7V61 · UniProt Q695T7 · UniProt Q9BYF1
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