MolNFT v1 · #189103 · protein
Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 33
7V2J: “Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 33”. X-ray diffraction, 1 ligand (5FZ). MolNFT v1 #189103 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7V2J
- Type
- protein
- Length
- 131 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O60885
- Ligands
- 5FZ
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 131 | — | O60885 |
Ligands and binding sites
- 5FZ · ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-4-methoxy-benzenesulfonamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7V2J · Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 33 · the same entry in another collection · chain A against A, TM-score 1.00
- O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60885
- Elsewhere: RCSB PDB 7V2J · PDBe 7V2J · UniProt O60885
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.