MolNFT v1 · #188933 · protein
Crystal structure of HIV-1 integrase complexed with (2S)-2-(tert- butoxy)-2-(5-{2-[(2-chloro-6-M ETHYLPHENYL)METHYL]-1,2,3,4- tetrahydroisoquinolin-6-yl}-4- (4,4-dimethylpiperidin-1-yl)-2- methylpyridin-3-YL)ACETIC acid
7UOQ: “Crystal structure of HIV-1 integrase complexed with (2S)-2-(tert- butoxy)-2-(5-{2-[(2-chloro-6-M…”. X-ray diffraction, 2 ligands (O20, SO4). MolNFT v1 #188933 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7UOQ
- Type
- protein
- Length
- 140 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q76353
- Ligands
- O20, SO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 140 | — | Q76353 |
Ligands and binding sites
- O20 · (2S)-tert-butoxy[(5m)-5-{2-[(2-chloro-6-methylphenyl) methyl]-1,2,3,4-tetrahydroisoquinolin-6-yl}-4-(4,4-dimethylpiperidin-1-yl)-2-methylpyridin-3-yl]acetic acid · ligand · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7UOQ · Crystal structure of HIV-1 integrase complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q76353
- Elsewhere: RCSB PDB 7UOQ · PDBe 7UOQ · UniProt Q76353
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.