MolNFT v1 · #188809 · protein
Apo ribb from vibrio cholera
7UEZ · 3,4-dihydroxy-2-butanone 4-phosphate synthase: “Apo ribb from vibrio cholera”. X-ray diffraction, 3 pockets (best druggability 0.56). MolNFT v1 #188809 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7UEZ
- Type
- protein
- Length
- 396 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3,4-dihydroxy-2-butanone 4-phosphate synthase
- EC
- 4.1.99.12
- UniProt
- A0A0H6NPW4
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) | protein | 197 | 43% helix, 21% strand | A0A0H6NPW4 |
| B | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) | protein | 199 | 42% helix, 21% strand | A0A0H6NPW4 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 323 | 0.56 | 0.75 | 34 | empty |
| 2 | 275 | 0.54 | 0.76 | 31 | empty |
| 3 | 60 | 0.36 | 0.78 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 942 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 7UEZ · Apo RibB from Vibrio cholera · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H6NPW4
- Elsewhere: RCSB PDB 7UEZ · PDBe 7UEZ · UniProt A0A0H6NPW4
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