MolNFT v1 · #18864 · RNA
Hammerhead ribozyme with 5'-5' G-G linkage: conformational change experiment
1Q29 · 5'-R(*GP*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)- 3': “Hammerhead ribozyme with 5'-5' G-G linkage: conformational change experiment”. X-ray diffraction, 1 ligand (CO), 2 pockets (best druggability 0.32). MolNFT v1 #18864 on…
- PDB
- 1Q29
- Type
- RNA
- Length
- 41 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-R(*GP*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)- 3'; Ribozyme
- Ligands
- CO
- Pockets
- 2 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 5'-R(*GP*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)- 3' | rna | 17 | — | — |
| B | Ribozyme | rna | 24 | — | — |
Ligands and binding sites
- CO · Cobalt (II) ion · metal · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 98 | 0.32 | 0.73 | 10 | CO |
| 2 | 71 | 0.28 | 0.73 | 11 | CO |
Interfaces
1 interface between chains.
- A–B · 1004 Ų buried · 67 hydrogen bonds · nucleic-nucleic
Compared structures
- 1Q29 · Hammerhead Ribozyme with 5'-5' G-G linkage: Conformational change experiment · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1Q29 · PDBe 1Q29
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