MolNFT v1 · #188601 · protein + DNA

Structure of drid C-domain bound to 9MER ssdna

7TZV · Wyl domain-containing protein: “Structure of drid C-domain bound to 9MER ssdna”. X-ray diffraction, 3 pockets (best druggability 0.86). MolNFT v1 #188601 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7TZV
Type: protein + DNA
Length: 394 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Wyl domain-containing protein; DNA (5'-D(*TP*AP*GP*TP*CP*TP*AP*CP*T)-3')
UniProt: Q9A999
Pockets: 3 · best druggability 0.86

Structure

x-ray diffraction · 3 distinct chains · 31% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Wyl domain-containing protein	protein	193	31% helix, 36% strand	Q9A999
M	Wyl domain-containing protein	protein	192	30% helix, 36% strand	Q9A999
J	DNA (5'-D(TPAPGPTPCPTPAPCP*T)-3')	dna	9	—	—

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1054	0.86	0.87	74	empty
2	210	0.48	0.75	34	empty
3	88	0.32	0.74	14	empty

Interfaces

2 interfaces between chains.

A–M · 2697 Å² buried · 29 hydrogen bonds · protein-protein
A–J · 809 Å² buried · 28 hydrogen bonds · protein-nucleic

Compared structures

7TZV · Structure of DriD C-domain bound to 9mer ssDNA · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9A999
Elsewhere: RCSB PDB 7TZV · PDBe 7TZV · UniProt Q9A999

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