MolNFT v1 · #188554 · protein

Selenomethionine labeled structure of rext

7TXO · Transcriptional regulator: “Selenomethionine labeled structure of rext”. X-ray diffraction, 1 ligand (CL), 1 pocket (best druggability 0.32). MolNFT v1 #188554 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7TXO
Type: protein
Length: 203 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator
UniProt: Q8YVV6
Ligands: CL
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator	protein	102	51% helix, 15% strand	Q8YVV6
B	Transcriptional regulator	protein	101	49% helix, 13% strand	Q8YVV6

Ligands and binding sites

CL · Chloride ion · ion · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.32	0.76	16	empty

Interfaces

1 interface between chains.

A–B · 681 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

7TXO · Selenomethionine Labeled Structure of RexT · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8YVV6
Elsewhere: RCSB PDB 7TXO · PDBe 7TXO · UniProt Q8YVV6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.