MolNFT v1 · #188344 · protein
Crystal structure of zea mays inositol-tetrakisphosphate kinase 1 (ITPK1)
7TN5 · Inositol-tetrakisphosphate 1-kinase 1: “Crystal structure of zea mays inositol-tetrakisphosphate kinase 1 (ITPK1)”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.59). MolNFT v1 #188344 on GenesisL1: 3D structure…
- PDB
- 7TN5
- Type
- protein
- Length
- 269 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inositol-tetrakisphosphate 1-kinase 1
- EC
- 2.7.1.134, 2.7.1.159
- UniProt
- Q84Y01
- Ligands
- CL
- Pockets
- 2 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inositol-tetrakisphosphate 1-kinase 1 (EC 2.7.1.134, 2.7.1.159) | protein | 269 | 33% helix, 27% strand | Q84Y01 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 304 | 0.59 | 0.78 | 47 | empty |
| 2 | 79 | 0.38 | 0.77 | 20 | empty |
Compared structures
- 7TN5 · Crystal structure of Zea mays Inositol-tetrakisphosphate Kinase 1 (ITPK1) · the same entry in another collection · chain A against A, TM-score 1.00
- Q84Y01 · AlphaFold monomer V2.0 prediction for inositol-tetrakisphosphate 1-kinase 1 (Q84Y01) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q84Y01
- Elsewhere: RCSB PDB 7TN5 · PDBe 7TN5 · UniProt Q84Y01
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