MolNFT v1 · #18821 · protein
Anti-morphine antibody 9B1 unliganded form
1Q0X · Fab 9B1, light chain: “Anti-morphine antibody 9B1 unliganded form”. X-ray diffraction, 1 ligand (SO4), 5 pockets (best druggability 0.47). MolNFT v1 #18821 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1Q0X
- Type
- protein
- Length
- 427 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fab 9B1, light chain; Fab 9B1, heavy chain
- UniProt
- P01723
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | Fab 9B1, light chain | protein | 212 | 7% helix, 54% strand | P01723 |
| H | Fab 9B1, heavy chain | protein | 215 | 7% helix, 53% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 203 | 0.47 | 0.74 | 32 | empty |
| 2 | 93 | 0.41 | 0.77 | 13 | PG4 |
| 3 | 94 | 0.36 | 0.75 | 18 | empty |
| 4 | 61 | 0.28 | 0.74 | 20 | empty |
| 5 | 52 | 0.28 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- L–H · 1825 Ų buried · 22 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01723
- Elsewhere: RCSB PDB 1Q0X · PDBe 1Q0X · UniProt P01723
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