MolNFT v1 · #188061 · protein

Crystal structure of cyanophycin synthetase 2 from gloeothece citriformis

7TA5 · Glutathione synthase: “Crystal structure of cyanophycin synthetase 2 from gloeothece citriformis”. X-ray diffraction, 1 ligand (BCN), 4 pockets (best druggability 0.70). MolNFT v1 #188061 on GenesisL1: 3D structure, binding sites…

PDB: 7TA5
Type: protein
Length: 585 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutathione synthase
EC: 6.3.2.3
UniProt: B7KEP8
Ligands: BCN
Pockets: 4 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutathione synthase (EC 6.3.2.3)	protein	585	34% helix, 24% strand	B7KEP8

Ligands and binding sites

BCN · Bicine · ligand · chains A
TAR · D(-)-tartaric acid · additive · 2 copies · chains A
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	602	0.70	0.78	58	empty
2	398	0.67	0.80	43	empty
3	133	0.49	0.79	29	empty
4	155	0.41	0.74	30	TAR

Compared structures

7TA5 · Crystal structure of cyanophycin synthetase 2 from Gloeothece citriformis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B7KEP8
Elsewhere: RCSB PDB 7TA5 · PDBe 7TA5 · UniProt B7KEP8

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