MolNFT v1 · #188051 · protein
HIV integrase in complex with compound-25
7T9O: “HIV integrase in complex with compound-25”. X-ray diffraction, 2 ligands (GEI, SO4). MolNFT v1 #188051 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7T9O
- Type
- protein
- Length
- 138 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Integrase
- UniProt
- Q76353
- Ligands
- GEI, SO4
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Integrase | protein | 138 | 52% helix, 22% strand | Q76353 |
Ligands and binding sites
- GEI · (2S)-tert-butoxy[4-(4,4-dimethylpiperidin-1-yl)-5-{4-[2-(4-fluorophenyl)ethoxy]phenyl}-2,6-dimethylpyridin-3-yl]acetic acid · ligand · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7T9O · HIV Integrase in complex with Compound-25 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q76353
- Elsewhere: RCSB PDB 7T9O · PDBe 7T9O · UniProt Q76353
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