MolNFT v1 · #188015 · protein
Crystal structure of phosphoserine aminotransferase from klebsiella pneumoniae subsp. pneumoniae in complex with pyridoxal phosphate
7T7J: “Crystal structure of phosphoserine aminotransferase from klebsiella pneumoniae subsp. pneumoniae in complex…”. X-ray diffraction, 1 ligand (PLP), 9 pockets (best druggability 0.73). MolNFT v1 #188015 on GenesisL1: 3D structure…
- PDB
- 7T7J
- Type
- protein
- Length
- 717 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoserine aminotransferase
- EC
- 2.6.1.52
- UniProt
- A0A0H3GMA6
- Ligands
- PLP
- Pockets
- 9 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoserine aminotransferase (EC 2.6.1.52) | protein | 357 | 40% helix, 18% strand | A0A0H3GMA6 |
| B | Phosphoserine aminotransferase (EC 2.6.1.52) | protein | 360 | 40% helix, 19% strand | A0A0H3GMA6 |
Ligands and binding sites
- PLP · Pyridoxal-5'-phosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 448 | 0.73 | 0.83 | 46 | PLP |
| 2 | 490 | 0.71 | 0.81 | 49 | PLP |
| 3 | 56 | 0.52 | 0.87 | 19 | empty |
| 4 | 142 | 0.47 | 0.77 | 26 | empty |
| 5 | 117 | 0.44 | 0.77 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 2186 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 7T7J · Crystal Structure of Phosphoserine aminotransferase from Klebsiella pneumoniae subsp.… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H3GMA6
- Elsewhere: RCSB PDB 7T7J · PDBe 7T7J · UniProt A0A0H3GMA6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.