MolNFT v1 · #187934 · protein
Structure of unphosphorylated pediculus humanus (pH) PINK1 D334A mutant
7T3X · SERINE/THREONINE-protein kinase PINK1: “Structure of unphosphorylated pediculus humanus (pH) PINK1 D334A mutant”. X-ray diffraction, 4 pockets (best druggability 0.53). MolNFT v1 #187934 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7T3X
- Type
- protein
- Length
- 399 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/THREONINE-protein kinase PINK1
- EC
- 2.7.11.1
- UniProt
- E0W1I1
- Pockets
- 4 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase PINK1 (EC 2.7.11.1) | protein | 399 | 38% helix, 14% strand | E0W1I1 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 221 | 0.53 | 0.77 | 32 | empty |
| 2 | 111 | 0.40 | 0.75 | 15 | empty |
| 3 | 110 | 0.38 | 0.74 | 24 | empty |
| 4 | 104 | 0.36 | 0.74 | 18 | empty |
Compared structures
- 7T3X · Structure of unphosphorylated Pediculus humanus (Ph) PINK1 D334A mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E0W1I1
- Elsewhere: RCSB PDB 7T3X · PDBe 7T3X · UniProt E0W1I1
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