MolNFT v1 · #187901 · protein
JAK2 JH2 in complex with JAK292
7T1T: “JAK2 JH2 in complex with JAK292”. X-ray diffraction, 1 ligand (E8I). MolNFT v1 #187901 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7T1T
- Type
- protein
- Length
- 274 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O60674
- Ligands
- E8I
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 274 | — | O60674 |
Ligands and binding sites
- E8I · (2S)-2-[({4-[(2-amino-7H-pyrrolo[2,3-d]pyrimidin-4-yl) oxy]phenyl}carbamoyl)amino]-4-phenylbutanoic acid · ligand · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7T1T · JAK2 JH2 in complex with JAK292 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60674
- Elsewhere: RCSB PDB 7T1T · PDBe 7T1T · UniProt O60674
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