MolNFT v1 · #187864 · protein
Cryo-EM structure of OMPK36-tran mating pair stabilization proteins from carbapenem-resistant klebsiella pneumoniae
7SZI: “Cryo-EM structure of OMPK36-tran mating pair stabilization proteins from carbapenem-resistant klebsiella…”. Electron microscopy, 11 pockets (best druggability 0.85). MolNFT v1 #187864 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7SZI
- Type
- protein
- Length
- 1,038 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- OMPK36; Tran
- UniProt
- D6QLY0
- Pockets
- 11 · best druggability 0.85
Structure
electron microscopy · 4 distinct chains · 5% helix, 58% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | OMPK36 | protein | 342 | 5% helix, 58% strand | D6QLY0 |
| B | OMPK36 | protein | 345 | 6% helix, 59% strand | D6QLY0 |
| C | OMPK36 | protein | 342 | 5% helix, 58% strand | D6QLY0 |
| D | Tran | protein | 9 | 0% helix, 0% strand | — |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 254 | 0.85 | 0.95 | 32 | empty |
| 2 | 162 | 0.76 | 0.93 | 46 | empty |
| 3 | 540 | 0.74 | 0.82 | 54 | empty |
| 4 | 1052 | 0.70 | 0.75 | 74 | empty |
| 5 | 1066 | 0.70 | 0.74 | 73 | empty |
Interfaces
5 interfaces between chains.
- B–C · 1670 Ų buried · 27 hydrogen bonds · protein-protein
- A–C · 1661 Ų buried · 27 hydrogen bonds · protein-protein
- A–B · 1661 Ų buried · 29 hydrogen bonds · protein-protein
- C–D · 543 Ų buried · 12 hydrogen bonds · protein-protein
- A–D · 35 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7SZI · Cryo-EM structure of OmpK36-TraN mating pair stabilization proteins from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D6QLY0
- Elsewhere: RCSB PDB 7SZI · PDBe 7SZI · UniProt D6QLY0
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